Effects of Human Donor Milk on a Severely Malnourished Child

Effects of Human giver draw on a Severely Malnourished ChildAbstractHunan draw has many benefits, such(prenominal)(prenominal) as optimal fodder, easy digestibility and immunological protection for infants and contains more than or less growth factors that domiciliate protect immature tissue, fire maturation oddly of the gastro enteral tract and promote healing of alter tissue. The first military personnel race milk brim was set up in China last grade and had 36 recipients including preterm infants and different sick children. save the authors found close to almost unbelievable effects of gracious bestower milk in a severely malnourished child pursual intestinal surgery. This case demonstrates that human donor milk is not yet a food only if also an important therapy to some children with malnutrition.Keywordshuman milk, human milk bank, post-operative malnutritionBackgroundHuman milk has many benefits, such as optimal nutrition, easy digestibility and immunologi c protection for infants and contains some growth factors that canprotect immature tissue, promote maturation particularly of the gastrointestinal tract and promote healing of damaged tissue 1-3. Donor human milk (DHM) is the preferred feeding when the mothers have milk is not sufficient or not available. The first human milk bank was set up over 100 historic period ago . In air sick-timed infants DHM has been proven to be very hard-hitting for the prevention of infections and necrotizing enterocolitis (NEC), for reducing feeding intolerance and for improving long-term out causes 4-6. So, human milk banks are blossoming in North America and europium since the mid of 1980s. Since the first human milk bank was set up last year in China, DHM was used not only for preterm infants still also for children with other illnesses such as immune deficiency, malnutrition after intestinal surgery, cow milk allergy and serious infection. We have observed some amazing effects in sick child ren. The objective of this report is to break the case of a severely malnourished child following intestinal surgery.Case ReportXiao Jiang(an alias) was the first recipient of DHM from our milk bank. He was a 10-month old boy coming from Zhanjiang, a prefecture-level city in Guangdong province, China. He was admitted to the local hospital because of group AB distention. After laparotomy his condition deteriorated more and more with high fever, haemorrhage under the pelt, and weight loss from 9 kg to 5.5 kg. He developed a terrible intestine fistula and free rupture of the surgical incision. It seemed that at that place was no hope for survival and he was discharged from the hospital to home. Five solar days later, his parents took the boy to our hospital. On the second day after admission, by the surgeon in charge obtained a nutrition consultation because of the patients severe malnutrition. Unfortunately, there appeared to be intestinal bleeding as the ileostomy output became brown after consumption of a feeding bottle of formula( Fig 1 and Fig 2). So, he had to be given perfect parenteral nutrition until the intestinal active bleeding stopped on the 4th day in hospital. Then, we started the minimal enteral feeding with 10 ml DHM from our milk bank.MethodsWe gave him the DHM in a dose of only 10 ml after the intestinal bleeding stopped on the fifth day of admission and then gradually increased the amount by 20-30ml q3h daily until 130 ml q3h was reached ( table 1). Everyday we monitored whether he had vomiting, diarrhea, abdominal distension, and temperature, examined the abdominal wound and monitored ileostomy output and his general condition. At the same time, the patients weight was placed every day at first and every 5 day later.Table 1 Feeding strategy and weight change of XiaojiangResultsFrom the meaning Xiao Jiang was fed with human milk, seemingly magical effects were noted in this boy, with his fever subsiding and, petechiae and abdominal d istension disappearing. At the same time, his skin color became pink, his sleep became better and longer, his ileostomy output decreased markedly and became icteric in color like a normal babys stool. More unbelievably, granulation tissue grew out and his abdominal rupture healed within one week and his weight increased speedily from 5.5 kg to 7.15 kg within just 17 days. The seemingly magical changes are pictured below (Fig 3 and Fig 4) and documentedby the data in Table 1.DiscussionThe benefits of human milk in nourishing preterm infants have been sufficiently demonstrated in novel years. Since the first human milk bank was set up in 1909 milk banks have blossomed and grown rapidly in numbers in the past 30 years7. Pasteurized DHM has turn up to be an important remedial resource in the care of preterm infants. Although the milk banks primarily serve the needs of sick preterm babies, DHM is also used for paediatric conditions such as metabolic disorders, immunodeficiencies, s evere infections, severe allergies, failure to thrive, renal failure, various congenital conditions, postoperative therapy and cancer in adults 8-13. In recent years, human milk banks have demonstrated remarkable growth, and clinicians have come to value the importance of DHM not only as a nutritional option but also a potentially life-saving therapy14-19.Similarly, we have seen the short-run beneficial and possibly lifesaving clinical effects in other morbid infants and children, especially children with complications after intestinal surgery, exemplified by the case presented here. Our traditional nutrition knowledge could not explain these surprising medical results. So, what is the mechanism? Obviously, there are many areas among the benefits of heart-feeding and DHM which we should study further. Breast milk contains all the nutrients requisite for the growth and development of the infant. The protein, fat and calcium in breast milk are more easy for an infant to digest an d absorb than the ones in other milks. This may explain why breast milk can save a malnourished, dying boy like Xiao Jiang. It is estimated that more than 900 infants/year may be saved in the United States if 90% of mothers only when breastfed for 6 months. In developing countries exclusive breastfeeding for 6 months is the most potent intervention, potentially preventing more than 1 million infant deaths/year 20.Morever, breast milk is rich in substances that provide passive immunity to the baby, such as anti-infective factors, anti-inflammatory factors, immunomodulatory factors, hormones and multifunctional agents. Human milk it has been used as a home remedy for minor ailments, such as conjunctivitis, insect bites and stings, inter-group communication dermatitis, and infected wounds, burns, and abrasions. In 1990 Lucas et al. reported thatNEC was reduced significantly by breastfeeding premature infants, either exclusively or partially supplemented with either formula or pasteu rized DHM 21. From the case we report ,here, we can see the dramatic therapeutic effect against inflammation of surgical incisions.Of course, we need more research on human milk and DHM to understand the mechanisms by which human milk protects ill children and how it promotes recovery and growth in these circumstances. Such research has the potential to impart important new insights regarding the uniqueness and efficacy of human milk and the quality of breastfeeding in infant development while also identifying novel mechanisms for unhealthiness prevention and treatment.ConclusionDHM is not only the best food for preterm infants and other ill babies when their own mothers milk is not available, but also an important therapy for some severely ill children, such as severe post-operative malnutrition. We need more research to understand the mechanisms of the protection and therapeutic effects of DHM in such disease states.